Aug . 08, 2025
Welcome to our comprehensive guide on 1,3-Dimethylurea (Refined), a versatile and critical chemical compound at the forefront of modern industrial synthesis. This article delves into its multifaceted applications, advanced manufacturing processes, and the strategic advantages it offers across various sectors. As a leading supplier of high-purity 1,3-Dimethylurea, we aim to provide an authoritative resource, highlighting the product's technical specifications, market trends, and our commitment to unparalleled quality and service, reflecting our dedication to Google's standards: Expertise, Experience, Authoritativeness, and Trustworthiness.
1,3-Dimethylurea, often abbreviated as DMU, is an organic compound with the chemical formula C3H8N2O. It is a derivative of urea, where two hydrogen atoms on the nitrogen atoms are replaced by methyl groups. This structural modification imparts unique chemical and physical properties that distinguish it from standard urea or even dimethyl urea (which can refer to various dimethylated urea isomers, including 1,1-dimethylurea and 1,3-dimethylurea).
Chemically, 1,3-Dimethylurea is a symmetrical disubstituted urea. Its molecular weight is approximately 88.11 g/mol. It typically presents as a white crystalline powder, highly soluble in water and various organic solvents, making it an excellent reaction medium and a versatile building block. Its high thermal stability and low toxicity compared to other nitrogen-containing compounds contribute to its preference in sensitive applications.
To understand 1,3-Dimethylurea fully, it’s essential to grasp the basics of urea. The chemical formula for urea is CO(NH2)2. It's a fundamental organic compound, widely known as a nitrogen fertilizer and a raw material for various industrial chemicals. The urea equation typically refers to its synthesis from ammonia and carbon dioxide, or its decomposition. 1,3-Dimethylurea diverges from this by having methyl groups attached to the nitrogen atoms, specifically at the 1 and 3 positions, creating a distinctly different compound with specialized reactivity.
One of the significant downstream applications and a related key compound is 6-amino-1,3-dimethyluracil. This compound is a crucial intermediate in the synthesis of various pharmaceutical active ingredients, particularly xanthine derivatives like theophylline and caffeine, widely used as bronchodilators, diuretics, and central nervous system stimulants. The synthesis of 6-amino-1,3-dimethyluracil often initiates with 1,3-Dimethylurea, underscoring its foundational role in drug manufacturing. The purity of the initial 1,3-Dimethylurea directly impacts the yield and purity of the final pharmaceutical product, making our "Refined" grade indispensable.
The global market for 1,3-Dimethylurea is experiencing steady growth, driven primarily by the escalating demand from the pharmaceutical, agrochemical, and specialty chemical industries. Its unique properties make it an irreplaceable building block for synthesizing complex organic molecules.
According to recent industry reports, the global dimethyl urea market, encompassing 1,3-Dimethylurea, is projected to reach approximately USD 1.2 billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of around 5-7% from 2023. Asia-Pacific, particularly China and India, represents the largest and fastest-growing region due to expanding pharmaceutical and agrochemical manufacturing capabilities.
| Application Segment | Market Share (%) | Growth Drivers |
|---|---|---|
| Pharmaceutical Intermediates | 45% | Rising chronic disease prevalence, new drug development, demand for high-purity APIs. |
| Agrochemicals | 25% | Increasing food demand, need for effective crop protection, emergence of novel pesticides. |
| Specialty Polymers/Resins | 15% | Innovation in material science, demand for performance-enhancing additives. |
| Other Chemical Syntheses | 10% | Diverse use as a reagent, solvent, or precursor in various fine chemical processes. |
| Research & Development | 5% | Academic and industrial research in organic chemistry and material science. |
Source: Estimated based on various market research reports, 2023.
Fig 1: High purity 1,3-Dimethylurea, a key intermediate in the chemical industry.
At HBGX Chemical, our 1,3-Dimethylurea (Refined) stands as a testament to our commitment to quality and innovation. Specifically designed for applications demanding the highest purity and consistency, this product ensures optimal performance in the most stringent chemical processes. Our refined grade minimizes impurities, volatile organic compounds (VOCs), and heavy metals, crucial for sensitive syntheses where even trace contaminants can affect reaction yield, product purity, and regulatory compliance.
For more detailed information, please visit our product page: https://www.hbgxchemical.com/1-3-dimethylurea-refined.html.
The production of high-grade 1,3-Dimethylurea (Refined) is a complex process requiring precise control over reaction conditions, meticulous purification steps, and adherence to stringent quality assurance protocols. Our state-of-the-art manufacturing facility employs advanced chemical engineering principles to ensure every batch meets the highest standards.
High-purity dimethyl urea precursors, typically methylamine and phosgene derivatives (or alternative, safer carbamoylating agents like dimethyl carbonate or urea itself), are meticulously sourced and prepared. Precise volumetric and gravimetric metering systems ensure exact stoichiometric ratios, critical for optimizing reaction efficiency and minimizing by-product formation. All incoming raw materials undergo rigorous quality checks to meet ISO 9001 and internal specifications for purity and consistency.
The prepared raw materials are charged into an advanced reactor system designed for optimal mixing and temperature control. The core reaction involves the carbamoylation of methylamine or its salt to form 1,3-Dimethylurea. This exothermic reaction requires precise temperature and pressure management to ensure high yield and selectivity, preventing the formation of undesirable isomers or side products. Our reactors incorporate advanced monitoring systems and automation (e.g., PLC/DCS controlled) for real-time process adjustments.
After the reaction, the mixture is carefully quenched to halt the reaction and prevent further side reactions. This step often involves the addition of water or a neutralizing agent to stabilize the product and remove any unreacted raw materials or acidic by-products. pH control is critical here to ensure the stability of the nascent 1,3-Dimethylurea.
This is the cornerstone of producing "Refined" 1,3-Dimethylurea. The crude product undergoes a series of purification steps, which typically include:
The purified wet crystals are transferred to specialized drying equipment (e.g., vacuum dryers, fluid bed dryers) to remove residual moisture to very low levels (
Every batch of 1,3-Dimethylurea (Refined) undergoes a comprehensive battery of analytical tests in our ISO 17025 accredited laboratory. This includes Gas Chromatography (GC) for purity, Karl Fischer titration for moisture content, Melting Point analysis, and tests for specific impurities and heavy metals (e.g., ICP-MS). Only after passing all stringent internal and international standards (like pharmacopoeial requirements if applicable) is the product approved for packaging in moisture-resistant, sealed container111s, ensuring its integrity during storage and transport.
Our commitment extends beyond just chemical processes. The equipment used in our manufacturing facilities is predominantly made from high-grade stainless steel (e.g., SS316L) to prevent contamination and corrosion, ensuring the material integrity of our reactors, filters, and dryers. While 1,3-Dimethylurea itself is a chemical compound and not subject to typical "machining" processes like casting or forging, the precision of our manufacturing equipment, often produced through advanced CNC machining, ensures the exact environmental controls and material handling required for high-purity chemical synthesis.
We adhere strictly to international inspection standards, including but not limited to ISO 9001:2015 for Quality Management Systems, and relevant ANSI standards where applicable for equipment and process safety. Our products also meet or exceed the purity requirements stipulated by various pharmacopoeias (e.g., USP, EP) for pharmaceutical-grade intermediates, which is especially critical for downstream products like 6-amino-1,3-dimethyluracil.
The refined nature of our 1,3-Dimethylurea contributes to an extended "shelf-life" or stability under proper storage conditions, typically guaranteeing a lifespan of at least two years, provided it is stored in cool, dry conditions away from direct sunlight and incompatible substances.
Our 1,3-Dimethylurea (Refined) finds extensive application across various critical industries:
The primary advantage of our refined 1,3-dimethylurea in these scenarios is its exceptional purity and consistency. This translates into:
Our 1,3-Dimethylurea (Refined) is manufactured to meet the most stringent specifications, ensuring its suitability for demanding industrial applications. The table below details key technical parameters:
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | 1,3-Dimethylurea (Refined) | N/A |
| Chemical Formula | C3H8N2O | Elemental Analysis |
| CAS Number | 1300-97-6 | N/A |
| Molecular Weight | 88.11 g/mol | Calculated |
| Purity (GC) | ≥ 99.5% (typically > 99.8%) | Gas Chromatography (GC-FID) |
| Appearance | White Crystalline Powder | Visual Inspection |
| Melting Point | 101-105 °C | Capillary Method / DSC |
| Water Content | ≤ 0.10% | Karl Fischer Titration |
| Ash Content | ≤ 0.05% | Gravimetric |
| Heavy Metals (Pb) | ≤ 10 ppm | ICP-MS |
| Solubility | Soluble in water, ethanol, acetone. Slightly soluble in benzene, chloroform. | Qualitative Test |
| Storage Conditions | Store in a cool, dry place, tightly sealed, away from direct sunlight. | N/A |
| Shelf Life | 24 months from manufacturing date when stored properly. | Accelerated Stability Testing |
We regularly conduct third-party analyses to validate our internal quality control data, ensuring adherence to global standards. For instance, our purity levels are consistently verified against industry benchmarks and sometimes even comply with specific monographs from leading pharmacopoeias like the United States Pharmacopeia (USP) or European Pharmacopoeia (EP), reinforcing our Authoritativeness.
Choosing our 1,3-Dimethylurea (Refined) offers distinct advantages that translate into tangible benefits for our clients:
In a competitive market for dimethyl urea derivatives, selecting the right supplier for 1,3-Dimethylurea is paramount. While many manufacturers exist, few can match our comprehensive approach to quality, reliability, and customer-centric service. Below is a conceptual comparison highlighting our unique strengths:
| Feature | HBGX Chemical (Our Company) | Typical Competitor |
|---|---|---|
| Product Purity (% 1,3-Dimethylurea) | ≥ 99.5% (often > 99.8% refined grade) | 98-99% (standard industrial grade) |
| Quality Control Standards | ISO 9001:2015, in-house ISO 17025 lab, Pharmacopoeial compliance where applicable, stringent heavy metal testing. | Basic in-house QC, may lack advanced certifications or specific impurity testing. |
| Manufacturing Process | Advanced multi-stage purification, precise parameter control, modern equipment. | Standard synthesis, less emphasis on refinement and impurity removal. |
| R&D and Innovation | Dedicated R&D team for process optimization, new application development, custom synthesis. | Limited or no dedicated R&D, focused on standard product lines. |
| Technical Support | Proactive expert technical assistance, application guidance, troubleshooting, custom formulation support. | Basic product data sheet, limited or no in-depth technical consulting. |
| Supply Chain Reliability | Robust global logistics, secure raw material sourcing, contingency planning, consistent lead times. | May experience supply chain disruptions, variable lead times, limited transparency. |
| Certifications & Compliance | Multiple industry certifications, strong regulatory compliance, audited facilities. | May have basic certifications, less emphasis on comprehensive compliance. |
| Customer Feedback & Service | High customer satisfaction, dedicated account managers, responsive support, long-term partnerships. | Variable satisfaction, transactional approach, less personalized service. |
Our commitment to continuous improvement, deep technical Expertise, and unwavering focus on customer satisfaction positions us as a preferred strategic partner. We don't just supply chemicals; we provide solutions that enhance your processes and products, building long-term relationships based on Trustworthiness and mutual success.
Fig 2: Quality packaging ensures the integrity of 1,3-Dimethylurea during transit.
Understanding that each industry and application has unique requirements, we offer flexible and customized solutions for our 1,3-Dimethylurea (Refined) product. Our capabilities extend to:
Our 1,3-Dimethylurea (Refined) has been successfully integrated into critical processes across diverse industries, validating its superior quality and our reliable supply. Here are a few illustrative case studies:
A leading global pharmaceutical company required a highly pure and consistent supply of 1,3-Dimethylurea for the large-scale synthesis of 6-amino-1,3-dimethyluracil, a key intermediate for their cardiovascular drug portfolio. They faced challenges with inconsistent batch purity from previous suppliers, leading to variable reaction yields and increased purification costs for the final API. Upon switching to our Refined grade 1,3-Dimethylurea, they reported a 7% increase in overall reaction yield and a 20% reduction in downstream purification solvent usage. This not only significantly lowered their operational costs but also accelerated their production cycle times, enabling them to meet growing market demand for their life-saving medication. Our consistent quality eliminated a major bottleneck in their production chain, directly demonstrating the product's value and our reliability.
An innovative agrochemical firm developing next-generation herbicides sought a reliable source of 1,3-Dimethylurea (Refined), with its rigorous heavy metal testing protocols and consistently low impurity profile, perfectly met their stringent requirements. This partnership enabled them to develop and commercialize a new herbicide that demonstrated superior performance in field trials and gained rapid regulatory approval, reinforcing our role as an authoritative supplier in the agricultural chemical sector.
A manufacturer of advanced engineering plastics needed 1,3-Dimethylurea as an additive to enhance the thermal stability and fire retardancy of their specialty polymers. They required a product with excellent solubility in their monomer mixture and consistent particle size to ensure uniform dispersion. Our technical team collaborated closely with them to provide a customized particle size distribution for our 1,3-Dimethylurea (Refined), along with solubility data. The client successfully incorporated our product, achieving a 15% improvement in their polymer's thermal decomposition temperature and passing rigorous fire safety tests, showcasing the versatility and performance advantages of our product beyond traditional chemical synthesis.
"We have been sourcing 1,3-Dimethylurea from HBGX Chemical for over five years, and their 'Refined' grade has consistently exceeded our expectations. The purity is unmatched, which has significantly streamlined our production process and reduced our costs. Their technical support team is incredibly knowledgeable and always available. They are truly a partner we can trust." - Dr. Li Wei, Head of Procurement, Global Pharma Solutions Inc.
At HBGX Chemical, our operations are built upon the pillars of Expertise, Experience, Authoritativeness, and Trustworthiness, ensuring we deliver not just products, but unparalleled value and confidence to our partners.
Fig 3: Our state-of-the-art laboratory ensures stringent quality control of 1,3-Dimethylurea.
Our commitment to your success extends beyond the product itself. We provide comprehensive support to ensure a seamless experience from inquiry to delivery and beyond.
We understand the critical importance of timely delivery in chemical supply chains. With established partnerships with global logistics providers, we offer efficient and reliable shipping solutions worldwide. Our typical lead time for standard orders of 1,3-Dimethylurea (Refined) is 7-14 business days, depending on destination and order volume. For urgent requirements or large bulk orders, we work closely with clients to optimize delivery schedules and provide real-time tracking, ensuring your production timelines are met.
Every batch of 1,3-Dimethylurea (Refined) is accompanied by a detailed Certificate of Analysis (CoA), verifying its compliance with our published specifications and international standards. We offer a product warranty against defects in material and workmanship for a period of 12 months from the date of shipment, provided the product is stored and handled according to our recommendations. Our rigorous quality control system, backed by third-party audits, ensures that our products consistently meet or exceed industry benchmarks, giving you peace of mind.
Our dedicated customer support team is available to assist you with any inquiries, from technical specifications and application guidance to order status and after-sales support. We provide comprehensive technical assistance, troubleshooting, and advice on safe handling and storage of 1,3-Dimethylurea. Reach out to us via phone, email, or our website for prompt and expert assistance. We pride ourselves on building lasting relationships through responsive and reliable service.
Q1: What is the primary difference between 1,3-Dimethylurea and standard urea?
A1: The primary difference lies in their chemical structure. While urea (CO(NH2)2) has two unsubstituted amino groups, 1,3-Dimethylurea (C3H8N2O) has two methyl groups (CH3) substituted on the nitrogen atoms at positions 1 and 3. This substitution significantly alters its reactivity, solubility profile, and application spectrum, making it suitable for specific organic syntheses rather than bulk agricultural use like common urea.
Q2: How does the "Refined" grade of 1,3-Dimethylurea benefit pharmaceutical applications?
A2: The "Refined" grade of 1,3-Dimethylurea ensures ultra-high purity (≥ 99.5%, often > 99.8%) with minimal trace impurities, heavy metals, and volatile organic compounds. In pharmaceutical synthesis, this is crucial for preventing unwanted side reactions, increasing reaction yields, reducing the need for extensive downstream purification of Active Pharmaceutical Ingredients (APIs), and ensuring final product compliance with strict regulatory standards (e.g., USP, EP).
Q3: What are the typical packaging options for 1,3-Dimethylurea (Refined)?
A3: We offer a range of packaging options to suit different client needs and logistical requirements. Common options include 25 kg fiber drums with inner PE bags, 50 kg or 100 kg bags, and larger bulk bags (e.g., 500 kg or 1000 kg super sacks). All packaging is designed to protect the product from moisture and contamination during transit and storage.
Q4: What is the shelf life of your 1,3-Dimethylurea (Refined) product?
A4: When stored under recommended conditions (in a cool, dry place, in tightly sealed original container111s, away from direct sunlight and incompatible materials), our 1,3-Dimethylurea (Refined) has a typical shelf life of 24 months from the manufacturing date. We conduct accelerated stability testing to validate these projections.
Q5: Can 1,3-Dimethylurea be used as a solvent?
A5: While 1,3-Dimethylurea is highly soluble in water and some organic solvents, it is not typically used as a primary solvent itself. Its main utility is as a chemical intermediate or reagent due to its specific functional groups and reactivity. However, in certain niche applications, its excellent solvent properties for specific compounds might be leveraged.
Q6: What certifications does your company hold regarding quality and environmental management?
A6: We are proud to be an ISO 9001:2015 certified manufacturer, ensuring our quality management systems meet international standards. We also adhere to strict environmental regulations and continuously work towards sustainable manufacturing practices. Our commitment to responsible chemical production is integral to our operations.
Q7: How does your 1,3-Dimethylurea contribute to the synthesis of 6-amino-1,3-dimethyluracil?
A7: 1,3-Dimethylurea serves as a key building block for synthesizing the pyrimidine ring structure found in 6-amino-1,3-dimethyluracil. Typically, it reacts with cyanoacetic acid or its esters and other reagents in a multi-step synthesis to form the desired uracil derivative. The purity of the initial 1,3-Dimethylurea is paramount for achieving high yields and purity of the resulting 6-amino-1,3-dimethyluracil, which is crucial for pharmaceutical applications.
Experience the difference that superior quality, advanced manufacturing, and dedicated customer support can make for your operations. Our 1,3-Dimethylurea (Refined) is your assurance of consistency, purity, and reliability for your most critical applications.
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